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Literature summary extracted from

  • Hirashima, M.; Tanaka, R.; Tanaka, A.
    Light-independent cell death induced by accumulation of pheophorbide a in Arabidopsis thaliana (2009), Plant Cell Physiol., 50, 719-729.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.14.15.17 additional information pheophorbide a, a key intermediate of chlorophyll catabolism, causes cell death in complete darkness in a transgenic Arabidopsis plant, As-ACD1. Expression of mRNA for pheophorbide a oxygenase is suppressed by expression of Acd1 antisense RNA. As-ACD1 accumulates an excessive amount of pheophorbide a when chlorophyll breakdown occurs. When senescence is induced by a continuous dark period, leaves of As-ACD1 plants become dehydrated, phenotype, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.15.17 additional information Arabidopsis thaliana the enzyme is involved in breakdown of pheophorbide a in chlorophyll degradation, involvement of pheophorbide a in the signaling pathway for programmed cell death, overview ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.17 Arabidopsis thaliana Q9FYC2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.15.17 leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.17 additional information the enzyme is involved in breakdown of pheophorbide a in chlorophyll degradation, involvement of pheophorbide a in the signaling pathway for programmed cell death, overview Arabidopsis thaliana ?
-
 ?

Expression

EC Number Organism Comment Expression
1.14.15.17 Arabidopsis thaliana Expression of mRNA for pheophorbide a oxygenase is suppressed by expression of Acd1 antisense RNA down

General Information

EC Number General Information Comment Organism
1.14.15.17 malfunction enzyme inhibition or downregulation leads to accumulation of pheophorbide a, a key intermediate of chlorophyll catabolism, which causes cell death in complete darkness in a transgenic Arabidopsis plant, As-ACD1. When senescence is induced by a continuous dark period, leaves of As-ACD1 plants become dehydrated, phenotype, overview Arabidopsis thaliana